Former Secretary of State, Hillary Clinton has become the first woman in US history to be nominated for president by any major party.
She reached the milestone in a roll call vote from all 50 states at the Democratic National Convention (DNC).
Mrs Clinton becomes the first woman to lead a ticket for a major United States party.
Hillary Clinton’s nomination comes after Senator Bernie Sanders’ supporters disrupted the first day of the convention with boos and jeers.
Party officials worked hard to ease tensions amid protest on the floor. Senator Sanders had sent out text messages and emails to delegates, urging them to stay calm.
Hillary Clinton First Female Presidential Candidate In US
Mrs Clinton passed the 2,382 delegates score needed to claim the nomination after South Dakota had announced its delegate vote count.
The former First Lady, New York Senator and Secretary of State was formally installed as the party nominee to take on Donald Trump on an emotional night at the Democratic convention in Philadelphia.
In a symbolic gesture of party unity, former Democratic rival Senator Bernie Sanders took the microphone to move to suspend the procedural rules and declare Mrs Clinton as the nominee by acclamation.
Chair of the Democratic National Committee, Congresswoman Marcia Fudge, approved the motion after a unanimous voice vote and members of the crowd erupted into cheers as they held up new Clinton signs.
Former President Bill Clinton is due to speak about his wife later on Tuesday, making the case for why she is qualified to take his old job.
Hillary will formally accept the nomination on Thursday night.
She will thereafter embark on an intense fall campaign, as polls presently show her clash with Republican nominee Trump is too close to call.
At the 2008 Democratic National Convention, Mrs Clinton had called for a vote for Barack Obama by acclamation. Ending the roll call vote in an effort to unite the party behind his candidacy.